Summary: Histone lysine demethylases (KDMs) play critical roles in oncogenesis and therefore may be effective targets for anticancer therapy. Using a time-resolved fluorescence resonance energy transfer demethylation screen assay. in combination with multiple orthogonal validation approaches. we identified geldanamycin and its analog 17-DMAG as KDM inhibitors. https://poolsproductscanadas.shop/product-category/vinyl-patch-kits/
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