BACKGROUND: Systemic leukocyte activation and disseminated leukocyte adhesion will impair the microcirculation and cause severe decrements in tissue perfusion and organ function in the process of severe sepsis. Gu-4. a lactosyl derivative. could selectively target CD11b to exert therapeutic effect in a rat model of severe burn shock. https://jeepworldes.shop/product-category/differential-covers/